- Miriam: A human who was bitten by a vampire. She claims to be queen of the vampires.
- Blade: Miriam's son, he is half human and half vampire. He possesses many of their abilities without their weaknesses, though he still requires plasma.
- Michael Morbius: A human who was bitten by a vampire bat that had become radioactive after drinking the blood of Peter Parker. He closely resembles a vampire though is different in several ways.
The history of vampires is unknown.
Censorship issues for Spider-Man meant they could not have a vampire that drank blood instead substituting plasma, which is a key component of blood. These same issues meant that Morbius had to suck plasma through suckers in his hands rather than his fangs.
Count Dracula is a figure in the Marvel universe, but here is he simply a fictional character in the series.
Vlad the Impaler is Count Dracula. No connection is made in any series.