|Alternate Identity|| Venom|
|Powers and Abilities||For Spider-Man: Enhances all powers. For Venom: Gives Eddie Brock all of Spider-Man's enhanced powers while nullifying Spider-Sense|
|Allies||Dormammu, Carnage, Spider-Man, Iron Man|
|Family and Friends||Carnage Symbiote (Offspring)|
The Venom Symbiote is an alien lifeform that attempts to take over other lifeforms that it needs to survive. It attached itself to Spider-Man as a suit and gained his powers and memories. He then rejected the symbiote and it bonded with Eddie Brock to become Venom. It also spawned the Carnage Symbiote.
- Peter Parker. The symbiote's first host.
- Random Woman. A man and his girlfriend walking through the park were attacked by the symbiote and its offspring.
- Eddie Brock. Joined together they become the villain Venom and seek revenge on Spider-Man.
The symbiote was on an asteroid when it was found by John Jameson. Jameson tried to get a piece of Prometheum X and the symbiote oozed out of the asteroid and tried to bond with Jameson. He returned to his shuttle and crashed onto the George Washington Bridge on Earth. The symbiote bonded with Spider-Man when they crashed into the Hudson River.
The symbiote became a new suit for him and began to take him over. He made Peter more aggressive but also more powerful. They defeated Rhino and Shocker but Spider-Man used a church bell to remove it. It then bonded to Eddie Brock and became Venom. They attacked Spider-Man but he used the John Jameson Space Probe to remove it from Eddie. He then webbed the symbiote to the shuttle.
While in space it reproduced another symbiote.
Dormammu ordered Baron Mordo to bring the shuttle back to Earth. When it landed it bonded with a passing woman while the other symbiote bonded with a man. The woman went to the Ravencroft Asylum for the Criminally Insane where it bonded with Eddie once again.
They attacked a Stark Enterprise presentation and fought Spider-Man. The other symbiote bonded with Eddie's cellmate Cletus Kasady to form Carnage. They defeated Spider-Man but were stopped by War Machine.
Venom and Carnage got the portal generator but fought each other. Dr. Ashley Kafka convinced Eddie to separate thanks to Curt Connors. However, Eddie rebonded with the symbiote to assist Spider-Man and Iron Man in defeating Carnage, Dormammu, and Mordo. However, to do so Eddie had to sacrifice himself.
In the other dimension, Venom and Carnage got past their differences and teamed up. They formed the Synobtic. They attacked a shuttle carrying John Jameson and left to Counter-Earth where they tried to take over the planet. Spider-Man followed and tried to stop them. The symbiote was once again separated from Eddie but Spider-Man was forced to bring them together again.
In the Comics
Spider-Man got the symbiote during the Secret Wars after his costume was damaged.
When Eddie is captured, he still has the symbiote as Venom.
Eddie's ex-wife Ann Weying briefly had the symbiote.